Neuropathological staging of AD-related changes in Increasing density of shading indicates increasing Outer two thirds of the molecular layer ofĭevelopment of neurofibrillary tangles and neuropil threadsįrom transentorhinal to isocortical stages. In Alzheimer’s disease, there is a prominent neurofibrillary degeneration of LIIĬells in the EC and their terminals in the DG show neuritic plaques. OVERVIEW OF MAJOR INPUT-OUTPUT RELATIONSHIP OF THE HIPPOCAMPUS Projected on the human basal cortical surface (Heimer and G. SUMMARY OF CORTICAL AND AMYGDALOID INPUT TO THE HIPPOCAMPUS Of the medial corticohypothalamic tract (Palkovits and Zaborszky, 1979). Inset electron micrograph with degenerated terminal after ventral subicular lesion) in the arcuate nucleus Scheme, to show the origin, course (upper right inset silver impregnation) and termination (lower left Rather than simply providing generalized inhibition (SOMOGYI and Klausberger, 2005). Temporal structuring of the activity of pyramidal cells and their inputs via their respective target domain in a co-operative manner, This suggests a role for interneurones in the The respective compartments will receive GABAergic input at different time points. Because the different interneurones innervate distinct domains of the pyramidal cells, Interneurones belonging to different connectivity classes fire preferentially atĭistinct time points during a given oscillation. Target-domain in a brain-state-dependent manner. Interneurones of the same connectivity class show different firing activities and therefore modulate their specific postsynaptic Ripple oscillations.The spike probability plots show that during different network oscillations representing two distinct brain states, The cells have differential temporal firing patterns during theta and The schematic drawing summarizes the main synaptic connections in the CA1 area of pyramidal cells (blue), parvalbuminĮxpressing basket, axo-axonic, bistratified and O-LM cells. LT-lamina terminalis P-pallium PA-parasubiculum PR-presubiculum S-subiculum SRstriatal ridges TH-thalamus V3 3rd cventricle VL-lateral ventricle a-amygdala hhippocampal region s-septal region sl-sulcus limitansĬA1 field of the hippocampus in human, monkey and ratĪ: dentate gyrus: ML-molecular GLgranualr PL-polymorph layers. AC-choroideal area ĬG-cingulate gyrus ENT-entorhinal area HR-hippocampal rudiment HY-hypothalamus Stages to assume the shape illustrated in the subsequent figure. Parahippocampal gyrus (cortex): anterior part (entorhinal cortex andĪssociated perirhinal cortex (areas 35,36) posterior part that includes TF andĪ: midsagittal, B: horizontal C-D medial wall of the telencephalon to show how theĭentate gyrus (DG) and the Ammons’s horn (AH)may fold during progressively later Temporal gyrus OT olfactory tract PHGparahippocampal gyrus TP-temporal pole: 28atrophic entorhinal area (From G vanHoesen) Notch UHF-uncal hippocampal formation CFĬalcarine fissure HIP hippocampus ITG inferior Sulcus SS-sulcus semianularis TN-tentorial Gyrus POC-primary olfactory cortex RS- rhinal Sobotta, B: Broadmann C: Roland, In (C) the scheme isĬS-collateral sulcus FM fimbria GS-semilunar Median sagittal surface of the human (A, B,) brain. Bulb 20-substantia nigra 22-corpus callosum (splenium) 23choroidal fissure 25-parahippocampal gyrus (From Insausti and Amaral, 2004)ġ-rhinal sulcus 2-collateral sulcus 3-intrrhinal sulcus 5-gyrus ambiens 6-entorhinalĬtx 8-uncus 9-hippocampal fissure 10-sulcus semiannularis 11-gyrus semilunaris 12mammillary bodies 13-anterior commissure 14-precommissural fornix 15. semiannularis 12- mammillaryīodies 17-optic chisam 18-olfactory tract 19-olf. 1-rhinal sulcus 2-collateral sulcus 3-intrrhinal sulcus 4-occipitotemoral sulcus 5-gyrus ambiens 6-entorhinalĬtx 7-perirhinal ctx, anterior portion 8-uncus 9-hippocampal fissure 10-s.
0 kommentar(er)
